The Relative Potency of Carcinogenic Tars and Oils
نویسندگان
چکیده
منابع مشابه
Toxicity and carcinogenic potency.
In our recent paper,‘’) we called attention to some of the points raised by Wlupple and by Zeise, Crouch, and Wilson. Our interest in this subject developed as we began analyzing our database of animal carcinogenesis bioas~ays.(*~~)In our analyses, we used as a measure of carcinogenic potency, the TD,,, defined as the dose rate (in mg/kg/body wt/day) which, if administered chronically for a sta...
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A tabulation of carcinogenic potency (TD50) by species for 492 chemicals that induce tumors in rats or mice is presented. With the use of the Carcinogenic Potency Database, experimental results are summarized by indicating in which sex-species groups the chemical was tested and the respective evaluations of carcinogenicity. A comparison of three summary measures of TD50 for chemicals with more ...
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Many phenols have carcinogenic activity. The Estonian shale oils contain up to 40 vol % phenols. The promoting activity after initiation of phenols of Estonian shale oils was tested in mice with a single subthreshold dose (0.36 mg) of benzo(a)pyrene. C57Bl and CC57Br mice were used in skin painting experiments. Weak carcinogenic activity was found in the total crude water-soluble phenols recove...
متن کاملThe Tab-separated Carcinogenic Potency Database (CPDB)
This tab-separated database is derived from the Carcinogenic Potency Database (CPDB) of Gold et al. that has been published in several earlier papers. This tab-separated database includes the same information as the plot version, and therefore the methods and guide to the plot provide details on what is summarized here. The CPDB is a single standardized resource of the results of 45 years of ch...
متن کاملGuide to the Screen Version of the Carcinogenic Potency Database
This guide to the screen version of the CPDB plot is intended to facilitate use of the data. The same results are reported as in the 2-sided published plots. The plot includes results of 6153 experiments on 1485 chemicals, and is organized alphabetically by chemical name. The plotted logarithmic scale of TD50s included in the published plot format is not included here. Experiments are listed un...
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ژورنال
عنوان ژورنال: Epidemiology and Infection
سال: 1930
ISSN: 0950-2688,1469-4409
DOI: 10.1017/s0022172400010111